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Why individual dosing matters

Rachael Rapinoe

November 12, 2020 3 min read


Why individual dosing matters

With a low and slow approach and these tried and true tips, each individual can experiment to find the right amount of CBD that works best for them.


What's right for me?

How much CBD is right for me? This is one of the questions we hear most often from our community. First, we’ll share with you some tried and true tips and then some helpful tools to build an individualized game plan that’s just right for you.

Let us start by assuring you that CBD and THC are non-addictive or habit forming in any way. Nor is there evidence that you can overdose on CBD. In fact, in 2017, the World Health Organization released a report on the benefits and safety of cannabidiol, and concluded that CBD is well-tolerated in humans even at doses as high as 1500 mg CBD daily.

So when we discuss optimal dosage, we are really focusing on how to maximize the positive benefit of the product while minimizing any adverse reactions from taking too much at one time. Generally speaking, there is no need for concern of dependence or overdosing.


low and slow

Our Mendi mantra is to go ‘low & slow’ when starting out with either our No THC CBD Line or Full Spectrum CBD Line. A good rule of thumb for all ingestible (Gummies, Gel Caps, Tinctures) is to start at a dosage of 25mg. Our Gummies and Gel caps contain 25mg of CBD per serving and our Tinctures have a dropper that allows you to tailor the dose precisely to meet your needs.

For topical products (Cream, Salve Stick, Massage Oil) you can lather generously, as these products will provide more targeted relief and do not enter the bloodstream. They can be applied liberally based on the severity of your symptoms, every 2-3 hours.

Once you feel comfortable with a 25mg dose you can continue to increase your dose slowly. Effective doses can range from 5mg to 100mg at a time. And some studies suggest the benefit of CBD may increase up to the point of taking 1mg of CBD per lb of body weight, daily.

While CBD is well tolerated, some people may experience symptoms such as a dry mouth or lethargy if they have taken too much CBD at one time. If you experience this, we recommend reducing your next dose for a better experience.

Unlike some prescription drugs, there is little evidence of tolerance build-up with CBD usage. In fact, the limited evidence actually suggests the opposite is true - longtime users can actually find benefits in smaller doses.


not A one-size-fits all

CBD dosing is a personal thing. Like any medication or supplement, there are a variety of factors that impact what is effective for each person. Here are some of the factors to consider:

  • Your sensitivity to other medications or supplements
  • Your previous experience with CBD
  • Your body weight
  • Your desired effect
  • Severity of your symptoms
  • Your metabolism and body chemistry if taking an ingestible
  • Allergies - CBD isn’t known to cause allergic reaction, but look at the other natural ingredients in a product before using

It can take a little time to find the right dosage and mix of products that work best for you. Consider using these steps as you experiment:

  • Keep a journal or log of what you took, dosage, and the effects
  • Take a few small doses over the course of the day rather than one big dose
  • Use the same dose and ratio for several days before adjusting
  • Remember that small doses tend to stimulate; large doses sedate

If you’re taking prescriptions medications, talk to your doctor or health professional to determine an amount appropriate for you, or if there are any conflicting effects to be aware of.


Learn from others

Our customers constantly provide us with new ways they've found Mendi to help them. Hear some of the latest Ah-hah! Moments from our community’s +700 reviews.


Eager to learn more? There is still a lot of research to be done on CBD, dosing, and its effects We encourage you to do some research on your own if you are interested:

Project CBD

WHO 2017 Report

Journal of Cannabinoid Medicine

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